Fifth meeting of the Transgenic Rat ImmunoPhenomic platform of Nantes

                                                          “Advances in transgenic animal models and techniques”

                                                                       11th and 12th May 2017, Nantes, France


May 11th


12h30-13h25: Registration and coffee

13h20-13h30: Welcome address- Ignacio Anegon


Session 1:  Genome engineering 1                                    


13h30-14h00.   Exploring Cas9 and CRISPR diversity for genome engineering applications. V. Siksnys, Vilnius University, Lithuania


14h00-14h30: The CRISPR-associated DNA-cleaving enzyme Cpf1.  I. Fonfara, Max-Planck-Institute for Infection Biology, Berlin.


14h30-15h00: Selected oral presentations from abstracts





15h00-15h30. Coffee break + poster exhibition + stands exhibitors


Session 2:  Generation of Transgenic Models 1


15h30-16h00. Genetically-modified mouse models: pros and cons of nucleases-based technologies. A. Fraichard, GenOway, Lyon, France


16h00-16h30. Rodent models in arterial hypertension research. A.M Geurts, Medical College of Wisconsin, Milwaukee, Wisconsin


16h30-17h00. Rodent models for atherosclerosis. A. Tedgui, Hôpital Européen Georges Pompidou, Paris, France.


17h00. End meeting day 1.


20h00. Meeting dinner




May 12th


Session 3:   Genome engineering 2


9h00-9h30. Epigenetic regulation and genomic engineering.  F. Stewart, Technische Universitat Dresden, Germany


9h30-10h00. New strategies for the genome editing of the rat. I. Anegon, INSERM 1064, Nantes, France.


10h00-10h30. New CRISPRs and Cas9 tools. C. Giovannangeli, Museum d’Histoire Naturelle, Paris, France


10h30-11h00. Coffee break + poster exhibition + stands exhibitors


Session 4: Generation of Transgenic Models 2


11h00–11h30.  Rodent models for the analysis of cognitive disorders. V. Brault, Institut Clinique de la Souris, Strasbourg, France.


11h30-12h00. Rodent models of muscular genetic diseases. C. Cadiou, Nantes University, Nantes, France


12h00-12h30: Selected oral presentations from abstracts





12h30-13h30. Lunch + Poster presentations + stand exhibitors


Session 5: Generation of Transgenic Models 3                                       


13h30-14h00. Pig models for preclinical therapies H. Niemann, Institute of Farm Animal Genetics, Neustadt, Germany.


14h00-14h30. Transgenic mosquitos. H. Hammond, Imperial College, London, UK


15h00-15h30: Coffee Break


Session 6:  New technologies    


16h00-16h30. Electroporation increases the efficiency of model creation. T. Kaneko , Kyoto University, Kyoto, Japan.


16h30-17h00. Streptococcus thermophilus CRISPR-Cas9 systems enable specific editing of the human genome. M. Müller, University of Freiburg, Freiburg, Germany


17h00. End of meeting


Chairman: I. Anegon


Local Scientific Correspondent: Séverine Ménoret


Local Organizing Committee:       Séverine Rémy

                                                         Laurent Tesson

                                                         Tuan Huy Nguyen

                                                         Laurent David

                                                         Claire Usal

                                                         Vanessa Chenouard

                                                         Laure-Héléne Ouisse

                                                         Lucas Brusselle


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